| Measure | Value |
|---|
Simplified model for learning, with time sped up. cAMP = 1 minus the glucose level. CAP occupancy rises with cAMP. The share of time the operator is free rises with lactose (allolactose) for a normal repressor. Transcription = operator free × (5% without CAP, up to 100% with CAP). Beta galactosidase activity heads toward 1000 × transcription units. Left out: inducer exclusion (glucose also limits lactose entry), the permease feedback loop, the need for some beta galactosidase to make allolactose, and the three extra operators of the real lac region.
| Measure | Value |
|---|
Simplified model for learning. Chromatin access = (0.15 + 0.85 × acetylation) × (1 − 0.9 × methylation). Activator effect = activators ÷ 4 × (1 − 0.7 × methylation), since methyl groups block binding. Transcription = access × (0.05 + 0.95 × activator effect). mRNA level = transcription × (1 − 0.5 × miRNA). Translation = 1 − 0.85 × miRNA. Protein = mRNA × translation. Real genes differ in how strongly each dial matters.
Strains and conditions are randomly generated. Predict first, then watch: after you answer, the picture plays out what the repressor, CAP and RNA polymerase do. Merodiploid problems assume no glucose and that the inducer reaches the repressor.
Your job
Drag a card onto a box, or tap a card and then tap the box's name. Cards are buttons, so Tab and Enter work too.
Wrong picks are fine here. Each one tells you why.